Immunolocalization of Adhesion Molecules in Rheumatoid and Osteoarthritic Synovial Tissues
نویسندگان
چکیده
Title Immunolocalization of Adhesion Molecules in Rheumatoid and Osteoarthritic Synovial Tissues Author(s) Aoyagi, Takahiko; Eguchi, Katsumi; Nakashima, Munetoshi; Ida, Hiroaki; Furuichi, Itaru; Maeda, Kenji; Nagataki, Shigenobu; Iwasaki, Katsuro Citation Acta medica Nagasakiensia. 1993, 38(2-4), p.62-70 Issue Date 1993-12-25 URL http://hdl.handle.net/10069/15909 Right NAOSITE: Nagasaki University's Academic Output SITE
منابع مشابه
Palisading cells of rheumatoid nodules: comparison with synovial intimal cells.
OBJECTIVES The palisading cells of rheumatoid nodules share certain features with synovial intimal cells. The similarities between the two cell populations have been reassessed using new cytochemical markers. METHODS Cell populations in cryostat sections of non-inflamed, rheumatoid and osteoarthritic synovial tissues, and rheumatoid nodules were assessed for the presence of CD68, prolyl hydro...
متن کاملComparative immunolocalization studies of collagenase 1 and collagenase 3 production in the rheumatoid lesion, and by human chondrocytes and synoviocytes in vitro.
The degradation of fibrillar type II collagen is a major feature of cartilage destruction in rheumatoid arthritis (RA). Since collagenase 3 is produced by chondrocytes and preferentially degrades type II cartilage collagen, it seemed likely that this enzyme would have a prominent role in the destruction of rheumatoid joints. Using immunolocalization techniques, we have examined and compared the...
متن کاملYKL-39 (chitinase 3-like protein 2), but not YKL-40 (chitinase 3-like protein 1), is up regulated in osteoarthritic chondrocytes.
OBJECTIVE To investigate quantitatively the mRNA expression levels of YKL-40, an established marker of rheumatoid and osteoarthritic cartilage degeneration in synovial fluid and serum, and a closely related molecule YKL-39, in articular chondrocytes. METHODS cDNA array and online quantitative polymerase chain reaction (PCR) were used to measure mRNA expression levels of YKL-39 and YKL-40 in c...
متن کاملCONCISE REPORT YKL-39 (chitinase 3-like protein 2), but not YKL-40 (chitinase 3-like protein 1), is up regulated in osteoarthritic chondrocytes
Objective: To investigate quantitatively the mRNA expression levels of YKL-40, an established marker of rheumatoid and osteoarthritic cartilage degeneration in synovial fluid and serum, and a closely related molecule YKL-39, in articular chondrocytes. Methods: cDNA array and online quantitative polymerase chain reaction (PCR) were used to measure mRNA expression levels of YKL-39 and YKL-40 in c...
متن کاملمقایسه سطح پروتئین شوک حرارتی- 70 در مایع سینویال بیماران مبتلا به آرتریت روماتوئید و اوستئوآرتریت
Background: Heat-shock proteins are part of a strictly controlled biological system that allows organisms to respond to environmental stresses. Different proinflammatory cytokines are present in the synovial tissue of rheumatoid arthritis patients. Such tissues respond to stress and induce heat-shock proteins. In addition, synovial cells are exposed to mechanical stress caused by joint motion. ...
متن کامل